Transient B-cell depletion and regulatory T-cells mediation in combination with adenovirus mediated IGF-1 prevents and reverses autoimmune diabetes in NOD mice

• Главные авторы: Shujun Ye (Автор), Saimei Hua (Автор), Meiyang Zhou (Автор)
• Формат: ‌
• Опубликовано: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Type 1 diabetes (T1D) is one of the T cells mediated autoimmune diseases, although B cells also play an important role in the development. Both T cell and B cell targeted immunotherapies exhibited efficacies in preventing and reversing the T1D. Current study was performed to investigate the protecti...