Discovery of Small-Molecule Antagonists of Orexin 1/2 Receptors from Traditional Chinese Medicinal Plants with a Hypnotic Effect

• Autores principales: Jia He (Autor), Jing Fang (Autor), Yuxin Wang (Autor), Chengyu Ge (Autor), Shao Liu (Autor), Yueping Jiang (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2023-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Insomnia is an important public health problem. The currently available treatments for insomnia can cause some adverse effects. Orexin receptors 1 (OX₁R) and 2 (OX₂R) are burgeoning targets for insomnia treatment. It is an effective approach to screening...