BRD7 facilitates ferroptosis via modulating clusterin promoter hypermethylation and suppressing AMPK signaling in diabetes-induced testicular damage

• Main Authors: Yuehai Xiao (Author), Zongjian Liang (Author), Jun Qiao (Author), Zhiqiang Zhu (Author), Bei Liu (Author), Yuan Tian (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Diabetes mellitus (DM)-induced testicular damage is associated with sexual dysfunction and male infertility in DM patients. However, the pathogenesis of DM-induced testicular damage remains largely undefined. Methods A streptozotocin (STZ)-induced diabetic model and high glucose...