Development of ¹⁸F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging

• Main Authors: Rocío García-Vázquez (Author), Jesper Tranekjær Jørgensen (Author), Klas Erik Bratteby (Author), Vladimir Shalgunov (Author), Lars Hvass (Author), Matthias M. Herth (Author), Andreas Kjær (Author), Umberto Maria Battisti (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pretargeted PET imaging is an emerging and fast-developing method to monitor immuno-oncology strategies. Currently, tetrazine ligation is considered the most promising bioorthogonal reaction for pretargeting in vivo. Recently, we have developed a method to ¹⁸F-label ultrareact...