Lysosome-Targeted Biosensor for the Super-Resolution Imaging of Lysosome-Mitochondrion Interaction

• Main Authors: Han Wang (Author), Guiqian Fang (Author), Huimin Chen (Author), Maomao Hu (Author), Yajuan Cui (Author), Boyang Wang (Author), Yudong Su (Author), Yu Liu (Author), Bo Dong (Author), Xintian Shao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The interaction between lysosomes and mitochondria includes not only mitophagy but also mitochondrion-lysosome contact (MLC) that enables the two organelles to exchange materials and information. In our study, we synthesised a biosensor with fluorescence characteristics that can image ly...