Selective Janus kinase 1 inhibition resolves inflammation and restores hair growth offering a viable treatment option for alopecia areata

• Main Authors: Johan Mattsson (Author), Elisabeth Israelsson (Author), Karin Björhall (Author), Linda Fahlén Yrlid (Author), Kristoffer Thörn (Author), Anna Thorén (Author), Emelie Andersén Toledo (Author), Lisa Jinton (Author), Lisa Öberg (Author), Cecilia Wingren (Author), Sofia Tapani (Author), Sonya G. Jackson (Author), Gabriel Skogberg (Author), Anders J. Lundqvist (Author), Ramon Hendrickx (Author), Anders Cavallin (Author), Torben Österlund (Author), Neil P. Grimster (Author), Magnus Nilsson (Author), Annika Åstrand (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Janus Kinase (JAK) inhibition has recently demonstrated therapeutic efficacy in both restoring hair growth and resolving inflammation in Alopecia Areata (AA). These effects are dose dependent and mainly efficacious at ranges close to a questionable risk profile. Objectives We exp...