The contribution of cell surface FcRn in monoclonal antibody serum uptake from the intestine in suckling rat pups

• Main Authors: Philip R Cooper (Author), Connie M Kliwinski (Author), Robert A Perkinson (Author), Edwin eRagwan (Author), John R Mabus (Author), Gordon D Powers (Author), Haimanti eDorai (Author), Jill eGiles-Komar (Author), Pamela J Hornby (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The neonatal Fc Receptor (FcRn) in intestinal epithelium is the primary mechanism for transfer of maternal immunoglobulin G (IgG) from suckled milk to serum; but the factors contributing to the rapid uptake of IgG are poorly understood. These studies help to determine the contribution of cell-surfac...