Gene therapy for diabetic peripheral neuropathy: A randomized, placebo‐controlled phase III study of VM202, a plasmid DNA encoding human hepatocyte growth factor

• 主要な著者: John A. Kessler (著者), Aziz Shaibani (著者), Christine N. Sang (著者), Mark Christiansen (著者), David Kudrow (著者), Aaron Vinik (著者), Nari Shin (著者), the VM202 study group (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2021-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract VM202 is a plasmid DNA encoding two isoforms of hepatocyte growth factor (HGF). A previous phase II study in subjects with painful diabetic peripheral neuropathy (DPN) showed significant reductions in pain. A phase III study was conducted to evaluate the safety and efficacy of VM202 in DPN....