Effects of Slow-Acting Metformin Treatment on the Hormonal and Morphological Thyroid Profile in Patients with Insulin Resistance

• Main Authors: Rosita A. Condorelli (Author), Rossella Cannarella (Author), Antonio Aversa (Author), Livia Basile (Author), Ottavia Avola (Author), Aldo E. Calogero (Author), Sandro La Vignera (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metformin appears to reduce TSH levels in untreated hypothyroid patients. In contrast, in euthyroid patients with type 2 diabetes mellitus (T2DM), metformin is initially devoid of effects on TSH. However, it is followed by a significant reduction in TSH level after twelve months of treatment. Additi...