Five-year field results and long-term effectiveness of 20 mg/kg liposomal amphotericin B (Ambisome) for visceral leishmaniasis in Bihar, India.

• Main Authors: Sakib Burza (Author), Prabhat K Sinha (Author), Raman Mahajan (Author), María Angeles Lima (Author), Gaurab Mitra (Author), Neena Verma (Author), Manica Balasegaram (Author), Pradeep Das (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Visceral Leishmaniasis (VL; also known as Kala-azar) is an ultimately fatal disease endemic in Bihar. A 2007 observational cohort study in Bihar of 251 patients with VL treated with 20 mg/Kg intravenous liposomal amphotericin B (Ambisome) demonstrated a 98% cure rate at 6-months. Between...