CD9 promotes TβR2-TβR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia

• Main Authors: Wanqi Huang (Author), Ze Zhang (Author), Xin Li (Author), Qingqing Zheng (Author), Chao Wu (Author), Luojia Liu (Author), Ying Chen (Author), Jiaping Zhang (Author), Xupin Jiang (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background During wound healing, fibroblast to myofibroblast transition is required for wound contraction and remodeling. While hypoxia is an important biophysical factor in wound microenvironment, the exact regulatory mechanism underlying hypoxia and fibroblast-to-myofibroblast transition...