Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

• 主要な著者: Natalia Avaliani (著者), Ulrich Pfisterer (著者), Andreas Heuer (著者), Malin Parmar (著者), Merab Kokaia (著者), My Andersson (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2017-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Direct conversion of human somatic cells to induced neurons (iNs), using lineage-specific transcription factors has opened new opportunities for cell therapy in a number of neurological diseases, including epilepsy. In most severe cases of epilepsy, seizures often originate in the hippocampus, where...