Biostimulatory effects of simvastatin on MDPC-23 odontoblast-like cells

• Main Authors: Maria Luísa de Alencar e Silva Leite (Author), Diana Gabriela Soares (Author), Fernanda Gonçalves Basso (Author), Josimeri Hebling (Author), Carlos Alberto de Souza Costa (Author)
• Format: Book
• Published: Sociedade Brasileira de Pesquisa Odontológica, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract: The aim of this study was to evaluate the bioactivity and cytocompatibility of simvastatin (SV) applied to MDPC-23 odontoblast-like cells. For this purpose, MDPC-23 cells were seeded in 96-well plates and submitted to treatments with 0.01 or 0.1 μM of SV for 24 h, 72 h or continuously thro...