PPARδ agonist protects against osteoarthritis by activating AKT/mTOR signaling pathway-mediated autophagy

• Main Authors: Guantong Sun (Author), Xiaodong Li (Author), Pengcheng Liu (Author), Yao Wang (Author), Cheng Yang (Author), Shuhong Zhang (Author), Lei Wang (Author), Xiaoqing Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is the most prevalent degenerative joint disease, and PPARs are involved in its pathogenesis; however, the specific mechanisms by which changes in PPARδ impact the OA pathogenesis yet to be discovered. The purpose of this study was to ascertain how PPARδ affects the onset and dev...