The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach.

• Main Authors: Scott R Fry (Author), Michelle Meyer (Author), Matthew G Semple (Author), Cameron P Simmons (Author), Shamala Devi Sekaran (Author), Johnny X Huang (Author), Catriona McElnea (Author), Chang-Yi Huang (Author), Andrea Valks (Author), Paul R Young (Author), Matthew A Cooper (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Serological tests for IgM and IgG are routinely used in clinical laboratories for the rapid diagnosis of dengue and can differentiate between primary and secondary infections. Dengue virus non-structural protein 1 (NS1) has been identified as an early marker for acute dengue, and is typi...