Diagnostic value of IHC and FISH methods for HER2 gene amplification detection in paraffin embedded blocks of breast cancer

Introduction: Breast cancer is the leading cause of malignancy related deaths in women worldwide. In 20%-30% of breast cancers, HER2 gene amplification or overexpression is observed. Determination of HER2 amplification is performed mainly by IHC technique to measure its protein expression on the cel...

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Main Authors: Seyed Ahmad Aleyasin (Author), Esmaeil Akbari (Author), Fatemeh Saadati (Author)
Format: Book
Published: Mashhad University of Medical Sciences, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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