Effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology induced by the fetal urogenital sinus implants

• Main Authors: Mingsan Miao (Author), Shuo Tian (Author), Ming Bai (Author), Liling Xiang (Author), Jianlian Gao (Author)
• Format: Book
• Published: Elsevier, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Aim: The research was to study the effect of Motherwort total alkaloids on the prostate hyperplasia mice model of pathological changes of related tissue morphology. Results: Compared with the model group(MG), Motherwort total alkaloid high, medium dose group(HD, MD) could significantly reduced the pathological changes of the prostate (P < 0.01); Finasteride(FG) and Motherwort total alkaloid low dose group(LD) could significantly reduce the pathological changes of the prostate (P < 0.05); Longbishu capsules(LG), Finasteride, Motherwort total alkaloid medium dose group could significantly reduce the pathological changes of the kidney (P < 0.01); Motherwort total alkaloid low dose group could significantly reduce the pathological changes of the kidney (P < 0.05); Motherwort total alkaloids could improve the pathological changes of the thymus and spleen. Conclusion: Motherwort total alkaloid can improve the pathological changes of prostatic hyperplasia in mice. Keywords: Motherwort total alkaloids, Prostate hyperplasia, Mice model, Prostate, Kidney, Thymus, Spleen

Item Description

1319-0164
10.1016/j.jsps.2017.04.030