Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo

• Main Authors: Dustin J. Flanagan (Author), Nick Barker (Author), Cameron Nowell (Author), Hans Clevers (Author), Matthias Ernst (Author), Toby J. Phesse (Author), Elizabeth Vincan (Author)
• Format: Book
• Published: The Company of Biologists, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The gastric epithelium consists of tubular glandular units, each containing several differentiated cell types, and populations of stem cells, which enable the stomach to secrete the acid, mucus and various digestive enzymes required for its function. Very little is known about which cell signalling...