Bmi1 Severs as a Potential Tumor-Initiating Cell Marker and Therapeutic Target in Esophageal Squamous Cell Carcinoma

• Main Authors: Xiaochen Wang (Author), Kang Li (Author), Maosheng Cheng (Author), Ganping Wang (Author), Hui Han (Author), Fangfang Chen (Author), Wenjing Liao (Author), Zhi Chen (Author), Jianwen Chen (Author), Yong Bao (Author), Liang Peng (Author), Demeng Chen (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2020-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Esophageal squamous cell carcinoma (ESCC) is a frequent malignant tumor with low 5-year overall survival. Targeting ESCC tumor-initiating cells (TICs) may provide a new research avenue to achieve better therapeutic effects of ESCC. However, the identity and characteristics of ESCC TICs remain poorly...