Evaluation of Marbofloxacin in Beagle Dogs After Oral Dosing: Preclinical Safety Evaluation and Comparative Pharmacokinetics of Two Different Tablets

• Prif Awduron: Zhixin Lei (Awdur), Qianying Liu (Awdur), Bing Yang (Awdur), Haseeb Khaliq (Awdur), Saeed Ahmed (Awdur), Bowen Fan (Awdur), Jiyue Cao (Awdur), Qigai He (Awdur)
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• Cyhoeddwyd: Frontiers Media S.A., 2018-04-01T00:00:00Z.
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The current study evaluates a tested marbofloxacin tablet (MBT) (Petsen), in terms of bioavailability and pharmacokinetics (PK) in a comparison of the commercialized and standard tablet (Marbocyl) in beagle dogs. Four different bacterial species were selected for the determination of the minimal inh...