Investigation of the Effect on the Albumin Binding Moiety for the Pharmacokinetic Properties of ⁶⁸Ga-, ^205/206Bi-, and ¹⁷⁷Lu-Labeled NAPamide-Based Radiopharmaceuticals

• Main Authors: Dániel Szücs (Author), Judit P. Szabó (Author), Viktória Arató (Author), Barbara Gyuricza (Author), Dezső Szikra (Author), Imre Tóth (Author), Zita Képes (Author), György Trencsényi (Author), Anikó Fekete (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although radiolabeled alpha-melanocyte stimulating hormone-analogue NAPamide derivatives are valuable melanoma-specific diagnostic probes, their rapid elimination kinetics and high renal uptake may preclude them from being used in clinical settings. We aimed at improving the pharmacokinetics of radi...