Investigation of the Effect on the Albumin Binding Moiety for the Pharmacokinetic Properties of ⁶⁸Ga-, ^205/206Bi-, and ¹⁷⁷Lu-Labeled NAPamide-Based Radiopharmaceuticals

• Principais autores: Dániel Szücs (Autor), Judit P. Szabó (Autor), Viktória Arató (Autor), Barbara Gyuricza (Autor), Dezső Szikra (Autor), Imre Tóth (Autor), Zita Képes (Autor), György Trencsényi (Autor), Anikó Fekete (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Although radiolabeled alpha-melanocyte stimulating hormone-analogue NAPamide derivatives are valuable melanoma-specific diagnostic probes, their rapid elimination kinetics and high renal uptake may preclude them from being used in clinical settings. We aimed at improving the pharmacokinetics of radi...