Resibufogenin Targets the ATP1A1 Signaling Cascade to Induce G2/M Phase Arrest and Inhibit Invasion in Glioma

• Main Authors: Xun Zhang (Author), Zhong Yao (Author), Zhiyi Xue (Author), Shuai Wang (Author), Xuemeng Liu (Author), Yaotian Hu (Author), Yan Zhang (Author), Jian Wang (Author), Xingang Li (Author), Anjing Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Resibufogenin (RB) is a major active ingredient in the traditional Chinese medicine Chansu and has garnered considerable attention for its efficacy in the treatment of cancer. However, the anticancer effects and underlying mechanisms of RB on glioblastoma (GBM) remain unknown. Here, we found that RB...