4-Anilinoquinazoline-based benzenesulfonamides as nanomolar inhibitors of carbonic anhydrase isoforms I, II, IX, and XII: design, synthesis, in-vitro, and in-silico biological studies

• Κύριοι συγγραφείς: Hossam Nada (Συγγραφέας), Ahmed Elkamhawy (Συγγραφέας), Magda H. Abdellattif (Συγγραφέας), Andrea Angeli (Συγγραφέας), Chang Hoon Lee (Συγγραφέας), Claudiu T. Supuran (Συγγραφέας), Kyeong Lee (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Human carbonic anhydrase inhibitors (hCAIs) are a key therapeutic class with a multitude of novel applications such as anticonvulsants, topically acting antiglaucoma, and anticancer drugs. Herein, a new series of 4-anilinoquinazoline-based benzenesulfonamides were designed, synthesised, and biologic...