In vitro evaluation of cutaneous penetration of acyclovir from semisolid commercial formulations and relation with its effective antiviral concentration

• Main Authors: Rafaela Martins Sponchiado (Author), Leticia Malgarim Cordenonsi (Author), Nathalie Ribeiro Wingert (Author), Bibiana Verlindo de Araujo (Author), Nadia Maria Volpato (Author)
• Format: Book
• Published: Universidade de São Paulo.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT The evaluation of drug permeation/penetration of semisolid formulations into animal skin can be useful to supplement the pharmaceutical equivalence. This paper describes the in vitro assessment of acyclovir (ACV) into porcine skin from commercial formulations with etermination of drug conce...