Generation of Human-Induced Pluripotent Stem Cells by a Nonintegrating RNA Sendai Virus Vector in Feeder-Free or Xeno-Free Conditions

• Main Authors: Chad C. MacArthur (Author), Andrew Fontes (Author), Namritha Ravinder (Author), David Kuninger (Author), Jasmeet Kaur (Author), Matthew Bailey (Author), Antje Taliana (Author), Mohan C. Vemuri (Author), Pauline T. Lieu (Author)
• Format: Book
• Published: Hindawi Limited, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The generation of induced pluripotent stem cells (iPSCs) from somatic cells has enabled the possibility of providing unprecedented access to patient-specific iPSC cells for drug screening, disease modeling, and cell therapy applications. However, a major obstacle to the use of iPSC for therapeutic a...