Bilateral Paraventricular Nucleus Upregulation of Extracellular Superoxide Dismutase Decreases Blood Pressure by Regulation of the NLRP3 and Neurotransmitters in Salt-Induced Hypertensive Rats

• Автори: Qing Su (Автор), Xiao-Jing Yu (Автор), Xiao-Min Wang (Автор), Hong-Bao Li (Автор), Ying Li (Автор), Juan Bai (Автор), Jie Qi (Автор), Nianping Zhang (Автор), Kai-Li Liu (Автор), Yan Zhang (Автор), Guo-Qing Zhu (Автор), Yu-Ming Kang (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Aims: Long-term salt diet induces the oxidative stress in the paraventricular nucleus (PVN) and increases the blood pressure. Extracellular superoxide dismutase (Ec-SOD) is a unique antioxidant enzyme that exists in extracellular space and plays an essential role in scavenging excessive reactive oxy...