A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against <i>S. pneumoniae</i> in Mice
Combining amoxicillin with the immunostimulatory toll-like receptor 4 agonist monophosphoryl lipid A (MPLA) represents an innovative approach for enhancing antibacterial treatment success. Exploiting pharmacokinetic and pharmacodynamic data from an infection model of <i>Streptococcus pneumonia...
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Main Authors: | Sebastian Franck (Author), Robin Michelet (Author), Fiordiligie Casilag (Author), Jean-Claude Sirard (Author), Sebastian G. Wicha (Author), Charlotte Kloft (Author) |
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Format: | Book |
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MDPI AG,
2021-03-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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