Selective decrease of components of the creatine kinase system and ATP synthase complex in chronic Chagas disease cardiomyopathy.

• Main Authors: Priscila Camillo Teixeira (Author), Ronaldo Honorato Barros Santos (Author), Alfredo Inácio Fiorelli (Author), Angelina Morand Bianchi Bilate (Author), Luiz Alberto Benvenuti (Author), Noedir Antonio Stolf (Author), Jorge Kalil (Author), Edecio Cunha-Neto (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Chronic Chagas disease cardiomyopathy (CCC) is an inflammatory dilated cardiomyopathy with a worse prognosis than other cardiomyopathies. CCC occurs in 30 % of individuals infected with Trypanosoma cruzi, endemic in Latin America. Heart failure is associated with impaired energy metaboli...