Development of a Promising ¹⁸F-Radiotracer for PET Imaging Legumain Activity In Vivo

• Päätekijät: Chunmei Lu (Tekijä), Xiuting Wang (Tekijä), Qiqi Wang (Tekijä), Lixia Zhang (Tekijä), Jianguo Lin (Tekijä), Ling Qiu (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Legumain has been found overexpressed in several cancers, which serves as an important biomarker for cancer diagnosis. In this research, a novel fluorine-18 labeled radioactive tracer [¹⁸F]<b>SF-AAN</b> targeting legumain was designed and synthesized for positron e...