Characterization of a novel HLA-A*11:335 allele resulting from a rare interlocus recombination involving HLA-A*11:01:01:01/126 and HLA-H*02:07/14/18 alleles with nanopore sequencing, in a volunteer from the China Marrow Donor Program

• Auteurs principaux: Li-Qun Zhang (Auteur), Erik Rozemuller (Auteur), Dan Wang (Auteur), Xiang-Jun Liu (Auteur), Jian-Ping Cai (Auteur)
• Format: Livre
• Publié: BMC, 2022-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background The major histocompatibility complex (MHC) in humans includes three classical class I loci (A, B, and C), which are important biomarkers for the transplantation of organs and hematopoietic stem cells. In the MHC, polymorphism is known to be extremely high while interlocus recombi...