Exploring the therapeutic potential of isoorientin in the treatment of osteoporosis: a study using network pharmacology and experimental validation

• Main Authors: Bo Zhang (Author), Zechao Qu (Author), Hua Hui (Author), Baorong He (Author), Dong Wang (Author), Yong Zhang (Author), Yiwei Zhao (Author), Jingjun Zhang (Author), Liang Yan (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Isoorientin (ISO) is a glycosylated flavonoid with antitumor, anti-inflammatory, and antioxidant properties. However, its effects on bone metabolism remain largely unknown. Methods In this study, we aimed to investigate the effects of ISO on receptor activator of nuclear factor-κ...