CXCR3 chemokine receptor contributes to specific CD8+ T cell activation by pDC during infection with intracellular pathogens.

• Main Authors: Camila Pontes Ferreira (Author), Leonardo Moro Cariste (Author), Isaú Henrique Noronha (Author), Danielle Fernandes Durso (Author), Joseli Lannes-Vieira (Author), Karina Ramalho Bortoluci (Author), Daniel Araki Ribeiro (Author), Douglas Golenbock (Author), Ricardo Tostes Gazzinelli (Author), José Ronnie Carvalho de Vasconcelos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemokine receptor type 3 (CXCR3) plays an important role in CD8+ T cells migration during intracellular infections, such as Trypanosoma cruzi. In addition to chemotaxis, CXCR3 receptor has been described as important to the interaction between antigen-presenting cells and effector cells. We hypothe...