Gene design, optimization of protein expression and preliminary evaluation of a new chimeric protein for the serological diagnosis of both human and canine visceral leishmaniasis.

• Main Authors: Wagner J T Santos (Author), Diego H C Tavares (Author), Artur L Castro Neto (Author), Marília B Nascimento (Author), Rafael Dhalia (Author), Alessandra L Albuquerque (Author), Carlos H N Costa (Author), Franklin B Magalhães (Author), Antônio M Rezende (Author), Osvaldo P de Melo Neto (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Visceral leishmaniasis (VL) is a major neglected disease, potentially fatal, whose control is still impaired by inefficient and/or expensive treatment and diagnostic methods. The most promising approach for VL diagnosis uses serological assays with recombinant proteins...