Modified TPP-MoS₂ QD Blend as a Bio-Functional Model for Normalizing Microglial Dysfunction in Alzheimer's Disease

• Autori principali: Ohoud A. Alomari (Autore), Safaa Qusti (Autore), Maha Balgoon (Autore), Fadwa Aljoud (Autore), Khalid A. Alamry (Autore), Mahmoud A. Hussein (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2023-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease of old age. Accumulation of β-amyloid peptide (Aβ) and mitochondrial dysfunction results in chronic microglial activation, which enhances neuroinflammation and promotes neurodegeneration. Microglia are resident macrophages...