Different voltage dependence of ICaL blockade in nonselective IKr blockers causes their opposite effects on early afterdepolarization in drug-induced arrhythmia
Several false-positive results in the human ether-à-gogo-related gene test suggest that blockers of the rapid component of delayed rectifier K+ current (IKr) do not necessarily produce drug-induced arrhythmias. Specifically, the occurrence of early afterdepolarization (EAD) differs among IKr blocker...
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| Main Authors: | , |
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| Format: | Book |
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Elsevier,
2021-09-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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