The effect of microneedles on the skin permeability and antitumor activity of topical 5-fluorouracil
Topical 5-fluorouracil (5-FU) is approved for the treatment of superficial basal cell carcinoma and actinic keratosis. However, 5-FU suffers from poor skin permeation. Microneedles have been successfully applied to improve the skin permeability of small and large molecules, and even nanoparticles, b...
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Elsevier,
2014-02-01T00:00:00Z.
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