Increased circulating trimethylamine N-oxide plays a contributory role in the development of endothelial dysfunction and hypertension in the RUPP rat model of preeclampsia

• Autors principals: Hui Chen (Autor), Jiabao Li (Autor), Ning Li (Autor), Hongsheng Liu (Autor), Jiyun Tang (Autor)
• Format: Llibre
• Publicat: Taylor & Francis Group, 2019-04-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Objective: We examined whether trimethylamine-N-oxide (TMAO) plays a role in endothelial dysfunction and hypertension in the reduced uterine perfusion pressure (RUPP) rat model of preeclampsia (PE).  Methods: Normal pregnant rats and RUPP rats were treated without or with 3,3-Dimethyl-1-butanol (DMB...