Perm1 regulates CaMKII activation and shapes skeletal muscle responses to endurance exercise training

• Main Authors: Yoshitake Cho (Author), Shizuko Tachibana (Author), Bethany C. Hazen (Author), James J. Moresco (Author), John R. Yates, III (Author), Bernard Kok (Author), Enrique Saez (Author), Robert S. Ross (Author), Aaron P. Russell (Author), Anastasia Kralli (Author)
• Format: Book
• Published: Elsevier, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Endurance exercise training remodels skeletal muscle, leading to increased mitochondrial content and oxidative capacity. How exercise entrains skeletal muscle signaling pathways to induce adaptive responses remains unclear. In past studies, we identified Perm1 (PGC-1 and ERR induced regul...