Methyl Canthin-6-one-2-carboxylate Restrains the Migration/Invasion Properties of Fibroblast-like Synoviocytes by Suppressing the Hippo/YAP Signaling Pathway

• Главные авторы: Zongying Zhang (Автор), Yunhan Wang (Автор), Qiuyun Xu (Автор), Xiaorong Zhou (Автор), Yong Ling (Автор), Jie Zhang (Автор), Liming Mao (Автор)
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• Опубликовано: MDPI AG, 2023-10-01T00:00:00Z.
• Предметы: article
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Rheumatoid arthritis (RA) is an inflammatory condition that causes severe cartilage degradation and synovial damage in the joints with multiple systemic implications. Previous studies have revealed that fibroblast-like synoviocytes (FLSs) play a pivotal role in the pathogenesis of RA. The appropriat...