Remembering your A, B, C's: Alzheimer's disease and ABCA1

• Κύριοι συγγραφείς: Cutler T. Lewandowski (Συγγραφέας), Megan S. Laham (Συγγραφέας), Gregory R.J. Thatcher (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2022-03-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The function of ATP binding cassette protein A1 (ABCA1) is central to cholesterol mobilization. Reduced ABCA1 expression or activity is implicated in Alzheimer's disease (AD) and other disorders. Therapeutic approaches to boost ABCA1 activity have yet to be translated successfully to the clinic...