Worenine Prevents Solar Ultraviolet-Induced Sunburn by Inhibiting JNK2

• Main Authors: Juanjuan Xiao (Author), Hui Lu (Author), Tengfei Ma (Author), Xiaofang Ni (Author), Teding Chang (Author), Man Liu (Author), Nijie Li (Author), Peijiang Lu (Author), Changshu Ke (Author), Qin Tian (Author), Ling Zou (Author), Fei Wang (Author), Wei Wang (Author), Lu Zhang (Author), Ping Yuan (Author), Lin Liu (Author), Jianmin Zhang (Author), Fei Shi (Author), Qiuhong Duan (Author), Feng Zhu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Excessive solar ultraviolet (SUV) radiation often causes dermatitis, photoaging, and even skin cancer. In the pathological processes of SUV-induced sunburn, JNK is activated by phosphorylation, and it in turn phosphorylates its downstream transcription factors, such as ATF2 and c-jun. The transcript...