Cost-Effectiveness of Testing for NS5A Resistance to Optimize Treatment of Elbasvir/Grazoprevir for Chronic Hepatitis C in China

• Main Authors: Jinyu Liu (Author), Yu Zhang (Author), Bin Wu (Author), Sen Wang (Author), David Bin-Chia Wu (Author), Ruxu You (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Objectives: Baseline presence of nonstructural protein 5A (NS5A) resistance-associated variants can attenuate the efficacy of new direct-acting antivirals. A potential method to attain the higher efficacy would be to screen for NS5A polymorphisms prior to the initiation of therapy and to adjust the...