Acceleration of Functional Maturation and Differentiation of Neonatal Porcine Islet Cell Monolayers Shortly In Vitro Cocultured with Microencapsulated Sertoli Cells

• Main Authors: Francesca Mancuso (Author), Mario Calvitti (Author), Giovanni Luca (Author), Claudio Nastruzzi (Author), Tiziano Baroni (Author), Stefania Mazzitelli (Author), Ennio Becchetti (Author), Iva Arato (Author), Carlo Boselli (Author), Monique D. Ngo Nselel (Author), Riccardo Calafiore (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The limited availability of cadaveric human donor pancreata as well as the incomplete success of the Edmonton protocol for human islet allografts fasten search for new sources of insulin the producing cells for substitution cell therapy of insulin-dependent diabetes mellitus (T1DM). Starting from is...