LncRNA-RMST Functions as a Transcriptional Co-regulator of SOX2 to Regulate miR-1251 in the Progression of Hirschsprung's Disease

• Egile Nagusiak: Lingling Zhou (Egilea), Zhengke Zhi (Egilea), Pingfa Chen (Egilea), Chunxia Du (Egilea), Binyu Wang (Egilea), Xiang Fang (Egilea), Weibing Tang (Egilea), Hongxing Li (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Hirschsprung's disease (HSCR) is a congenital disorder characterized by the absence of enteric neural crest cells (ENCCs). LncRNA rhabdomyosarcoma 2-associated transcript (RMST) is essential for the growth and development of neuron. This study aimed to reveal the role of RMST in the pathogenesi...