Time‐to‐Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine‐Citrulline‐Monomethylauristatin E Antibody-Drug Conjugates

• Príomhchruthaitheoirí: Matts Kågedal (Údar), Divya Samineni (Údar), William R. Gillespie (Údar), Dan Lu (Údar), Bernard M. Fine (Údar), Sandhya Girish (Údar), Chunze Li (Údar), Jin Y. Jin (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Wiley, 2019-08-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Peripheral neuropathy (PN) is a common long‐term debilitating toxicity of antimicrotubule agents. PN was the most frequent adverse event resulting in dose modifications and/or discontinuation of treatment for valine‐citrulline‐monomethylauristatin E antibody-drug conjugates (ADCs) developed at Genen...