Inhibition of tartrate-resistant acid phosphatase 5 can prevent cardiac fibrosis after myocardial infarction

• Main Authors: Shujun Yang (Author), Liying Pei (Author), Zijie Huang (Author), Yinsheng Zhong (Author), Jun Li (Author), Yinghui Hong (Author), Huibao Long (Author), Xuxiang Chen (Author), Changqing Zhou (Author), Guanghui Zheng (Author), Chaotao Zeng (Author), Haidong Wu (Author), Tong Wang (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Myocardial infarction (MI) leads to enhanced activity of cardiac fibroblasts (CFs) and abnormal deposition of extracellular matrix proteins, resulting in cardiac fibrosis. Tartrate-resistant acid phosphatase 5 (ACP5) has been shown to promote cell proliferation and phenotypic tra...