In vitro and in vivo toxicity and antibacterial efficacy of melittin against clinical extensively drug-resistant bacteria

• Hoofdauteurs: Parvin Askari (Auteur), Mohammad Hasan Namaei (Auteur), Kiarash Ghazvini (Auteur), Mehran Hosseini (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2021-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Melittin is one of the most studied antimicrobial peptides, and several in vitro experiments have demonstrated its antibacterial efficacy. However, there is evidence showing melittin has non-promising effects such as cytotoxicity and hemolysis. Therefore, concerns about unwanted...