Preclinical characterization of the ADME properties of a surrogate anti-IL-36R monoclonal antibody antagonist in mouse serum and tissues

The decision to pursue a monoclonal antibody (mAb) as a therapeutic for disease intervention requires the assessment of many factors, such as target-biology, including the total target burden and its accessibility at the intended site of action, as well as mAb-specific properties like binding affini...

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Hoofdauteurs: Kip P. Conner (Auteur), Cinthia V. Pastuskovas (Auteur), Marcus Soto (Auteur), Veena A. Thomas (Auteur), Mylo Wagner (Auteur), Dan A. Rock (Auteur)
Formaat: Boek
Gepubliceerd in: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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