Promoter Methylation of Tumor Suppressors in Thyroid Carcinoma: A Systematic Review

• Main Authors: Sara Sheikkholeslami (Author), Marjan Zarif -Yeganeh (Author), Samaneh Farashi (Author), Fereidoun Azizi (Author), Sima Kheradmand Kia (Author), Ladan Teimoori-Toolabi (Author), Mehdi Hedayati (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The tumor suppressor genes play a critical role in cellular and molecular mechanisms such as cell cycle processes, cell differentiation and apoptosis. Aberrant DNA methylation of tumor suppressor genes and subsequent gene expression changes have shown to be involved in the initiation and...