Structure-Activity Relationship of Mono-Ion Complexes for Plasmid DNA Delivery by Muscular Injection

Structure-Activity Relationship of Mono-Ion Complexes for Plasmid DNA Delivery by Muscular Injection

The structure-activity relationship of mono-ion complexes (MICs) for plasmid DNA (pDNA) delivery by muscular injection is demonstrated. MICs were formed between pDNA and monocationic poly(ethylene glycol) (PEG) macromolecules. As monocationic PEGs, the ω-amide-pentylimidazolium (APe-Im) end-modified...

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Main Authors: Amika Mori (Author), Yuki Kobayashi (Author), Kei Nirasawa (Author), Yoichi Negishi (Author), Shoichiro Asayama (Author)
Format: Book
Published: MDPI AG, 2021-01-01T00:00:00Z.
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